Monday, March 17, 2008

Fw: Asbestos induced Pleural Plaques



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From: Search for mesothelioma diagnosis <rssfwd@rssfwd.com>
To: shell8377@yahoo.com
Sent: Tuesday, March 4, 2008 11:24:57 PM
Subject: Asbestos induced Pleural Plaques

Pleural Plaques & the consequences of the House of Lords Decision On 17th October 2007 the House of Lords held that asbestos related Pleural Plaques would no longer constitute a compensatable medical condition.

Mon, 03 Mar 2008 19:52:32 GMT

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Source: http://eastclifframsgate.blogspot.com/2008/03/asbestos-induced-pleural-plaques.html
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Fw: Asbestos exposure predicts cell cycle control gene promoter methylation in pleural mesothelioma.



----- Forwarded Message ----
From: HubMed - mesothelioma <rssfwd@rssfwd.com>
To: shell8377@yahoo.com
Sent: Tuesday, March 4, 2008 11:24:59 PM
Subject: Asbestos exposure predicts cell cycle control gene promoter methylation in pleural mesothelioma.

[1]Carcinogenesis. 2008 Feb 28;
Christensen BC, Godleski JJ, Marsit CJ, Houseman EA, Lopez-Fagundo CY, Longacker JL, Bueno R, Sugarbaker DJ, Nelson HH, Kelsey KT

Malignant pleural mesothelioma (MPM) is a rapidly fatal tumor with increasing incidence world-wide responsible for many thousands of deaths annually. Although there is a clear link between exposure to asbestos and mesothelioma, and asbestos is known to be both clastogenic and cytotoxic to mesothelial cells, the mechanisms of causation of MPM remain largely unknown. However, there is a rapidly emerging literature that describes inactivation of a diverse array of tumor suppressor genes (TSG) via promoter DNA CpG methylation in MPM, although the etiology of these alterations remains unclear. We studied the relationships among promoter methylation silencing, asbestos exposure, patient demographics, and tumor histology using a directed approach; examining six cell cycle control pathway TSGs in an incident case series of 70 MPMs. Promoter hypermethylation of APC, CCND2, CDKN2A, CDKN2B, HPPBP1, and RASSF1 were assessed. We observed significantly higher lung asbestos body burden if any of these cell cycle genes were methylated (p1, (p

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Source: http://www.hubmed.org/display.cgi?uids=18310086
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Fwd: LegalView Reports on Prominent Montana Democrat's Demand for Funds to ...



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From: Live Search News: asbestos cancer <rssfwd@rssfwd.com>
Date: Sun, Mar 16, 2008 at 1:56 AM
Subject: LegalView Reports on Prominent Montana Democrat's Demand for Funds to ...
To: mesothelioma77@gmail.com


PR.com - Vermiculate is mineral that in some instances contains asbestos, which through overexposure and inhalation can cause a deadly form of lung cancer known as mesothelioma.

Sat, 15 Mar 2008 06:51:00 GMT

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Source: http://www.pr.com/press-release/76457
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Fwd: No cause for alarm



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From: Live Search News: asbestos cancer <rssfwd@rssfwd.com>
Date: Sun, Mar 16, 2008 at 1:56 AM
Subject: No cause for alarm
To: mesothelioma77@gmail.com


Stillwater News Press - Exposure to asbestos via inhalation can cause lung cancer and mesothelioma (a rare cancer of the membranes lining the abdominal cavity and surrounding internal organs), which is why the caution tape was surrounding the area in Murray.

Sun, 16 Mar 2008 03:37:00 GMT

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Source: http://www.stillwater-newspress.com/osu/local_story_076000328.html?keyword=topstory
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