From: HubMed - asbestos cancer <rssfwd@rssfwd.com>
Date: Fri, Mar 28, 2008 at 3:16 PM
Subject: Visual scoring of atherosclerosis in chest computed tomography: findings among male construction workers.
To: mesothelioma77@gmail.com
[1]Acta Radiol. 2008 Apr; 49(3): 328-36
Hiltunen A, Kivisaari L, Leino-Arjas P, Vehmas T
BACKGROUND: Standard chest computed tomography (CT) examinations may contain valuable and underused information on atherosclerosis. PURPOSE: To study the retrospective scoring of chest atherosclerosis in CT studies performed for reasons other than cardiovascular. MATERIAL AND METHODS: Unenhanced CT images originally used for lung cancer screening of 505 male construction workers were retrospectively analyzed for chest atherosclerotic calcifications (coronary, aortic, and precervical artery origins). Findings were compared between those with a prediagnosed cardiovascular disease or diabetes (n = 180) and disease-free subjects (n = 325). RESULTS: Arterial calcifications (all) occurred among 96.6% of the subjects and coronary calcifications among 91.7%. The average total calcium score of the diseased subjects was 8.34 vs. 5.13 in the disease-free group (P
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Source: http://www.hubmed.org/display.cgi?uids=18365822
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Mesothelioma Diagnosis Info aGuide
Unlike lung cancer, there is no association between mesothelioma and smoking Malignancies involving mesothelial cells in these size cavities are known as malignant mesothelioma, which may be localized or diffuse. Its most basic site is the pleura (outer lining of the lungs and chest cavity), but it may also occur in the peritoneum (the lining of the abdominal cavity) or the pericardium (a sac that surrounds the heart).
In this disease, malignant cells develop in the mesothelium, a protective lining that covers utmost of the size's internal organs.
Mesothelial cells normally line the body cavities, including the pleura, peritoneum, pericardium, and testis. Malignant mesothelioma has also been linked to curing radiation using thorium dioxide and zeolite, a silicate in the soil.
Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. Mesothelioma is diagnosed by pathological examination from a biopsy. This is the end of a skill that usually begins with symptoms that send top-notch people to the doctor: a fluid build-up around the lungs (pleural effusions), shortness of breath, suffering in the chest, or aches and or swelling in the abdomen. The X-ray may reveal pleural thickening commonly seen after asbestos exposure and increases suspicion of mesothelioma. A history of exposure to asbestos may increase clinical suspicion for mesothelioma.
Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. A physical examination is performed, followed by chest X-ray and often lung function tests. Shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space are often symptoms of pleural mesothelioma.
Diagnosing mesothelioma is often difficult, because the symptoms are similar to those of a number of other conditions. Malignant mesothelioma is more absolute in men, with a male-to-female ratio of 3:1. Malignant mesothelioma is a rare type of cancer in which malignant cells are found in the sac lining the chest or abdomen.
Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.
Malignant mesothelioma is often just called simply Mesothelioma and is a aptitude of lung cancer that is quite rare. Perfectly malignant mesotheliomas set up complex karyotypes, with extensive aneuploidy and rearrangement of bunch chromosomes. It can also occur in children; however, these cases are not thought to be associated with asbestos exposure.
Malignant mesothelioma has a peak incidence 35-45 years after asbestos exposure.
Utmost people with malignant mesothelioma require worked on jobs where they breathed asbestos. Mesothelioma is a finesse of cancer that is almost always caused by previous exposure to asbestos
There are now a number of cancer treatment options convenient to mesothelioma patients. Extrapleural pneumonectomy for selected patients with very early stage disease may succeed recurrence-free survival, but the impact it has on overall survival is unknownat this time. The covet of radiation curing in pleural mesothelioma has been shown to discharge pain in the majority of patients that are treated. But unfortunately, the duration of symptom control is short-lived. Surgical resection has been relied upon because radiation and chemotherapy let been ineffective undistorted treatments.
Extrapleural pneumonectomy is a more extensive procedure and has a higher mortality rate. Recently, the mortality rate has been lowered to 3.8%. It involves dissection of the parietal pleura; division of the pulmonary vessels; and en bloc resection of the lung, pleura, pericardium, and diaphragm followed by reconstruction. It provides the best local control because it removes the all-out pleural sac along with the lung parenchyma.
With surgery alone, the recurrence rate is very high and super patients die after a few months. At least half the patients who allow local control with surgery make distant metastasis upon autopsy.
Ling Ling
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